The synthesis and characterization of novel MOFs is an area of active research because of their potential use in such diverse areas as gas storage, catalysis, chemical sensors and molecular separation (Dey et al., 2014 Kreno et al., 2012 Farha & Hupp, 2010 ). Further, derivatized imidazole-5-carboxylic acids have been shown to be angiotensin-converting enzyme (ACE) inhibitors (Jallapally et al., 2015 Li et al., 1998 Yanagisawa et al., 1996 ).Īs a result of the myriad binding modes available to imidazole ligands that bear carboxylic acid substituents, they have found use in the preparation of several metal organic frameworks, MOFs (Starosta & Leciejewicz, 2006 Yin et al., 2009, 2012 Sun & Yang, 2007 Sun et al., 2006 ). Recent studies have shown that imidazole and benzimidazole derivatives exhibit pharmacological activity in histamine signaling (Tichenor et al., 2015 Marson, 2011 ), and act as tau aggregation inhibitors for Alzheimer's disease (Bulic et al., 2013 ), and in the central nervous system (Robichaud et al., 2011 Sheffler et al., 2011 ). Imidazole-containing compounds find use in numerous pharmaceuticals including fungicides, antiviral agents, antiarrhythmics, antihistamines, and anthelmintics (Varala et al., 2007 Horton et al., 2003 López-Rodríguez et al., 1999 ). Both compounds exhibit extensive hydrogen bonding, including involvement of the tetrachloridozincate anion, resulting in interconnected chains of anions joined by water molecules. The geometric parameters of the ImHCO 2H + and the ImHCO 2 moieties are the same within the standard uncertainties of the measurements. H 2O, (II), is a co-crystal salt with six residues: two ImHCO 2H + cations, two formula units of the zwitterionic 1 H-imidazol-3-ium-4-carboxylate, ImHCO 2, one tetrachloridozincate anion and one water molecule disordered over two sites in a 0.60 (4):0.40 (4) ratio. ![]()
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